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Cell Potential of Isolated Outer Hair Cells as a Function of Extracellular K+Concentration

 

作者: Alfred H. Gitter,  

 

期刊: ORL  （Karger Available online 1993）
卷期: Volume 55, issue 1  

页码: 1-2

 

ISSN:0301-1569

 

年代: 1993

 

DOI:10.1159/000276343

 

出版商: S. Karger AG

 

关键词: Outer hair cells;Potassium;Cochlea;Hearing loss;Ménière’s disease

 

数据来源: Karger

 

摘要:

Outer hair cells were isolated from apical turns of the guinea pig cochlea. The membrane potential differences of cells in extracellular medium with 5.8, 14.0, 28.9 or 67.5 mmol/l of potassium were ––72.0 ± 0.6 (mean ± SEM, n = 93), ––50.1 ± 2.1 (n = 4), ––37.7 ± 0.5 (n = 73) or ––20.0 ± 1.5 mV (n = 16), respectively. Membrane depolarization can explain two thirds of the K+-induced shortening of isola

 

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