SummaryVarious treatments for essential hypertrichosis are available. The aim of this study is to present our experience with a simplified thoracoscope sympathicolysis technique in this disorder, and to confront our results with data in the literature. 35 consecutive patients (11 male, 24 female, age 12–44 years) with essential hyperhidrosis, refractory to“conventional”medical treatment presenting between August 1993 and May 1994 were studied. Bilateral D2-D3 sympathicolysis was performed using a simplified one-time bilateral thoracoscope procedure under general anaesthesia. Clinical scores, complications and side effects were recorded one week, one month and one year after the intervention. Severe hyperhidrosis was present in the hands in 100%, axillae in 66% and soles of the feet in 86% of patients. In one patient, only a unilateral intervention was possible due to pleural adhesions. In the other 34 patients, palmar hyperhidrosis was completely and permanently relieved in 100% of cases. Axillar hyperhidrosis was significantly improved after one year in 91 % of patients, 52% of which showed a complete disappearance of hyperhidrosis. Side effects and complications were minimal. There were no permanent pleural, neurological (Horner) or other sequellae. Patient satisfaction was invariably very high. These findings compare favourably with historical data in the literature.Acta Clin Belg. 1996; 51–4: 244–53