Alteration of the mutagenicity of human fecal extracts by hepatic microsomal enzymes
作者:
Marion Ehrich,
JamesE. Aswell,
TracyD. Wilkins,
期刊:
Journal of Toxicology and Environmental Health
(Taylor Available online 1981)
卷期:
Volume 7,
issue 1
页码: 107-115
ISSN:0098-4108
年代: 1981
DOI:10.1080/15287398109529962
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
Human fecal extracts contain substances mutagenic toSalmonella typhimuriumTA 100. The mutagenicity of these extracts con be reduced enzymatically by inducible mammalian microsomal enzymes. Liver homogenates from rats administered the polychlorinated biphenyl mixture Aroclor 1254 and corn oil were both effective, relative to the quantity of microsomal protein available in the enzyme preparation.
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