Characterization of Adenovirus Genome Type 7h: Analysis of Its Relationship to Other Members of Serotype 7
作者:
Adriana E. Kajon,
Goran Wadell,
期刊:
Intervirology
(Karger Available online 1992)
卷期:
Volume 33,
issue 2
页码: 86-90
ISSN:0300-5526
年代: 1992
DOI:10.1159/000150235
出版商: S. Karger AG
关键词: Acute respiratory infection;Adenovirus 7;Pairwise comigrating restriction fragments
数据来源: Karger
摘要:
Ad7h is a newly identified genome type associated with severe lower acute respiratory infections and has so far been isolated only in South America. To obtain a clue to its possible origin, the degree of restriction enzyme site homology between adenovirus genome type 7h and those representative of the three described genomic clusters (GC) for serotype 7 was studied by analysis of pairwise comigrating DNA restriction fragments (PCRF) after digestion with BamHI, BglI, BglII, BstEll, EcoRl, Hindlll, Hpal, SalI, Smal, Xbal, and Xho 90) were observed with any of the genome types grouped within GC3 or with Ad7g (the only member of GC2), so since Ad7h seems to be related to both members of GC2 and GC3, it could equally be considered to represent a new cluster or to end up grouped in either GC2 or GC3, depending on the results of further analysis.
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