Three varieties of rice (Oryza sativaL.) in the USDA World Collection were selected as potential sources of host plant resistance to the Angoumois grain moth,Sitotroga cerealella(Olivier) and crossed with the susceptible commercial cv. Vista. The resistant varieties were ‘Mutica’ (CI 12273), PI 160849, and CI 7097. The crosses were evaluated through three or five generations for resistance to the Angoumois grain moth and lesser grain borer,Rhyzopertha dominica(F.) in no-choice tests. In addition to these two species, rice weevil,Sitophilus oryzae(L.), red flour beetle,Tribolium castaneum(Herbst), andCryptolestesspp. were included in free-choice tests. Two crosses were studied through the F3generation. The cross with the most promising resistant parent (‘Mutica’) was studied through the F5generation. In all cases, resistance was heritable (i.e., insect response in one generation tended to predict a similar response in the next generation). This tendency grew stronger as plants selected for resistance or susceptibility over several successive generations became more homozygous. Resistance to the Angoumois grain moth strongly predicted resistance to the lesser grain borer. The main criterion used to evaluate resistance was insect survival from larva to adult. This was related to the condition of the hulls, but the Angoumois grain moth generally required longer to develop on resistant lines than on susceptible ones.