THE PREPARATION AND THE ANTIBACTERIAL AND ANTIFUNGAL PROPERTIES OF SOME SUBSTITUTED BENZYL ALCOHOLS
作者:
D. V. Carter,
P. T. Charlton,
A. H. Fenton,
J. R. Housley,
B. Lessel,
期刊:
Journal of Pharmacy and Pharmacology
(WILEY Available online 1958)
卷期:
Volume 10,
issue S1
页码: 149-159
ISSN:0022-3573
年代: 1958
DOI:10.1111/j.2042-7158.1958.tb10394.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
AbstractA number of substituted benzyl alcohols have been prepared and together with some related, commercially available, compounds have been tested for antibacterial and antifungal properties. The most active inhibitory compound was 3:4:5‐trichlorobenzyl alcohol followed by 4‐chloro‐3:5‐dimethyl‐, 3:4‐dichloro‐ and 2:4‐dichlorobenzyl alcohols, but saturated aqueus solutions of the last three compounds were more rapidly bactericidal. Pharmacological tests have shown that 2:4‐dichlorobenzyl alcohol
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