A four-bed central station that can be connected to any commercial intensive-care bedside monitor was developed. The system is based on a personal computer (IBM®-AT compatible) as a local unit and on a microcontroller Intel®8031 as a remote unit. Four ECG signals are low-pass filtered, multiplexed, sampled at 256-Hz per channel, 8-bit A/D converted, preprocessed, and converted to a serial format RS-232 by the remote unit. The real-time display of the signals is at the standard speed of 25 and 50 mm/sec. Heartrate, alarms, trend plots, and general patient data are shown on an Olivetti®M280 and EGA 13“ color monitor as the local unit. The communication speed was set at 57.6 Kbaud full duplex. Additionally, to reach standard monitoring sweep rates using a 13” screen with 640 x 350 pixels, an ECG data-compression algorithm was implemented in the remote unit. This unit can support up to eight input channels and can work with any personal computer, via RS-232, with the appropriate software. It also allows other signal preprocessing software that could be developed, such as QRS detection or ST segment quantification, to be loaded into its random access memory and to be run under PC command. The development of this system demonstrated the use of a widespread piece of commercial equipment, the PC, in a very specific application, CCU monitoring, assuring low-cost system implementation. This feature is particularly attractive in upgrading existing CCU units in less developed countries.