This paper describes a method to obtain isolated photoreceptors by means of enzymatic and mechanical dissociation of the whole retina ofOrconectes limosusand the application of patch‐clamp techniquetothese dissociated ommatidia. Several gigaseals and single‐channel currents were recorded, demonstrating the validity and suitability of the experimental protocol. The data reported provide a new element in the ≪single photoreceptor approach≫ to the study of phototransduction mechanisms in invertebrates. These results add another animal model to the few currently described in literature, in which the application of gigaseal techniques to isolated cells has proved useful in the study of ion channels gating.