Cassava bacterial blight (CBB) is a major problem of cassava in Uganda. It was first recorded in Terego County, Nile Province in 1976, and a disease survey indicated that CBB is now present in over half of the country. Losses of 90–100% have been observed on susceptible varieties in parts of the Nile, North and Eastern provinces. Symptoms include angular leaf spots, blight, wilt dieback and gum exudations. Planting of infected materials, rainfall, hailstorms, wind and insects are major factors in the spread of the disease. Restriction of movement of infected cassava cuttings to non-infected areas, planting of resistant varieties and healthy cuttings, encouragement of mixed cropping and crop rotation are recommended for control.