Abstract:KARDIO‐E is an expert system for the electrocardiographic diagnosis of heart arrhythmias. AT the present stage the system can be used as a helpful diagnostic tool in the routine assessment of ECG recordings in preventive or systematic examinations as, by cardiologist's estimation, its performance is equivalent to that of a specialist of internal medicine (non‐cardiologist) highly skilled in the reading of ECG recordings. The system is also useful for instruction of electrocardiography in education of all medical profiles. This paper presents the ECG diagnosis problem, the automatic generation of the system's knowledge base and a detailed description of the system. Results of on assessment study are also presen