Activity of glutathione peroxidase and glutathione reductase in the human lens related to age
作者:
RathbunWilliam B.,
BovisMagdaline G.,
期刊:
Current Eye Research
(Taylor Available online 1986)
卷期:
Volume 5,
issue 5
页码: 381-385
ISSN:0271-3683
年代: 1986
DOI:10.3109/02713688609025177
出版商: Taylor&Francis
数据来源: Taylor
摘要:
Lenses from 42 eye bank eyes were assayed for glutathione peroxidase and glutathione reductase activities. The activity of glutathione peroxidase, when considered as a function of age, was lowest in the neonate lens, increasing with age to reach maximal values in young adult lenses, and thereafter progressively decreasing with ages greater than 40 years. Glutathione reductase activity was little affected by age when expressed as activity per lens, per gram lens or per mg soluble protein, indicating that activity of this enzyme did not increase with lens size as would a representative lenticular protein. However, the activity of this enzyme per gram lens was among the highest of any species yet examined.
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