Serum Ferritin in Haemodialysis Patients: Role of Blood Transfusions and Haemochromatosis Alleles’ HLA A3, B7 and B14
作者:
E. Gómez,
F. Ortega,
R. Peces,
E. Gago,
R. Marín,
J. Alvarez Grande,
期刊:
Nephron
(Karger Available online 1984)
卷期:
Volume 36,
issue 2
页码: 106-110
ISSN:1660-8151
年代: 1984
DOI:10.1159/000183127
出版商: S. Karger AG
关键词: Iron stores;Ferritin;Haemochromatosis alleles;Blood transfusions;Haemodialysis
数据来源: Karger
摘要:
In 48 patients on maintenance haemodialysis (HD), serum ferritin (SF) levels were measured and compared with ‘haemochromatosis alleles’, (HA), HLA A3, B7 and B14. A positive correlation was found between high SF levels and the presence of HA. When patients who had received 10 or fewer blood transfusions were studied, it was observed that this correlation did not exist, but it was evident, however, in patients who had received more than 10 blood transfusions. After 14 months in which blood transfusions were restricted, no significant difference in SF was observed between HA carriers and the rest. Our findings suggest that repeated blood transfusions can cause high SF in HD patients, especially in those with HLA A3, B7 or B14 antigens. Among our patients, restriction of blood transfusions seems sufficient to decrease high SF lev
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