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Diagnosis of Sickle Cell Disease in Chronically Transfused Patients

 

作者: Douglas Oliveri,   Carole Ober,   Allen Horwitz,  

 

期刊: American Journal of Pediatric Hematology/Oncology  （OVID Available online 1992）
卷期: Volume 14, issue 1  

页码: 77-81

 

ISSN:0192-8562

 

年代: 1992

 

出版商: OVID

 

关键词: DNA diagnosis;Sickle cell disease;Transfusion

 

数据来源: OVID

 

摘要:

Standard electrophoretic methods for the diagnosis of hemoglobinopathies are confounded in individuals chronically transfused. We present the accurate diagnosis of sickle cell disease in two such transfused patients by the application of polymerase chain reaction technology to analyze patient's hemoglobin β-chain genes directly.

 

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