Multiplicity Reactivation in UV-Irradiated Herpes Simplex Type 1 Virus
作者:
Jaroslav Roubal,
Vladimír Vonka,
期刊:
Intervirology
(Karger Available online 1973)
卷期:
Volume 1,
issue 2
页码: 73-79
ISSN:0300-5526
年代: 1973
DOI:10.1159/000148834
出版商: S. Karger AG
关键词: Herpes simplex virus;Virus genetics;Multiplicity reactivation;Virus plaques
数据来源: Karger
摘要:
Exposure of a herpes simplex virus type 1 to UV light resulted in a multi-component survival curve. Plaques formed by the UV-irradiated virus were smaller than those induced by untreated virus. Maximum plaque counts in cultures inoculated with non-irradiated virus were obtained on the 4th day; when using irradiated virus, the plaque count continued to increase during the subsequent 4 days. These findings may reflect host cell repair. A non-linear relationship between plaque count and virus dilution, indicative of multiplicity reactivation, was observed in cultures infected with heavily irradiated virus.
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