Recurrent Disseminated Histoplasmosis
作者:
RICHARD MORRIS,
ROBERT BETTS,
R. DOUGLAS,
RALPH JACOX,
期刊:
Southern Medical Journal
(OVID Available online 1978)
卷期:
Volume 71,
issue 6
页码: 621-623
ISSN:0038-4348
年代: 1978
出版商: OVID
数据来源: OVID
摘要:
A patient who has had three distinct recurrences of disseminated histoplasmosis over 22 years is presented. Measurements of cellular and humoral immune response to histoplasmin antigens were compared with previously reported data. Although initially sulfisoxazole therapy led to regression of disease, over the past 13 years she has required three courses of amphotericin B, each time with resolution of signs and symptoms. Despite minimal evidence of a cellular or humoral immune response to this organism, the patient has done well. Although disseminated histoplasmosis is often a fatal disease, this woman has tolerated the infection well.
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