首页   按字顺浏览 期刊浏览 卷期浏览 Analysis of multivariate parallel-line bioassay with composite responses and composite ...
Analysis of multivariate parallel-line bioassay with composite responses and composite doses, using canonical corrlations

 

作者: Weiying Yuan,   Anant M. Kshirsagar,  

 

期刊: Journal of Biopharmaceutical Statistics  (Taylor Available online 1993)
卷期: Volume 3, issue 1  

页码: 57-71

 

ISSN:1054-3406

 

年代: 1993

 

DOI:10.1080/10543409308835048

 

出版商: Marcel Dekker, Inc.

 

关键词: Multivariate bioassays;Canonical variables;Composite response;Composite dose;Parallel-line bioassays;Relative potency;Incomplete block designs

 

数据来源: Taylor

 

摘要:

The use of a composite response to estimate the relative potency in a multivariate parallel–line bioassay is described by Finney (1). Occasionally a multivariate bioassay has multiple drugs also. Such a situation arises, for example, when a treatment contains several drugs. A procedure for combining multiple responses and combining multiple drugs is proposed in this paper, in order to obtain point and interval estimates of the relative potency. A composite response and a composite dose level for this purpose are obtained by using canonical analysis.

 

点击下载:  PDF (414KB)



返 回