Discontinuing contact lens wear may lead to significant fluctuations in corneal hydration, corneal curvature and refractive error. Only those subjects who showed changes in corneal hydration while wearing their lenses demonstrated corneal fluctuations when lens wear was discontinued. Measurements of corneal thickness and refractive error are good indicators of determining when corneal hydration has stabilized. On those subjects who showed significant fluctuations in curvature refractive error and hydration a new lens was refitted which prevented these fluctuations from occurring when lens wear was discontinued.