Lack of Evidence of Vertical Transmission of Human Immunodeficiency Virus Type 2 in a Sample of the General Population in Bissau
作者:
Anne-Grethe Poulsen,
Birgit Kvinesdal,
Peter Aaby,
Ida Lisse,
Adam Gottschau,
Kåre Mølbak,
Francisco Dias,
Edgar Lauritzen,
期刊:
Journal of Acquired Immune Deficiency Syndromes
(OVID Available online 1992)
卷期:
Volume 5,
issue 1
页码: 25-30
ISSN:0894-9255
年代: 1992
出版商: OVID
关键词: HIV-2;Epidemiology;Vertical Transmission;West Africa;Guinea-Bissau.
数据来源: OVID
摘要:
Twenty-nine human immunodeficiency virus type 2 (HIV-2) seropositive women identified in a cross-sectional study in Bissau in 1987 participated in a follow-up study in 1988, where each was matched for age and marital status with two HIV-2 seronegative women. Detailed information about all pregnancies was obtained. The HIV-2 seropositive women and their controls had similar mean numbers of pregnancies, live children, children who died, and abortions. The HIV-2 seropositive women did not have a greater risk of having had an abortion or a child who died than did the HIV-2 seronegative women. No difference in survival was seen between children born to HIV-2 seropositive and HIV-2 seronegative women. The H/S-ratios and CD4 numbers were lower in the seropositive group, but none had values lower than 0.4 and 0.4 x 109/L, respectively. Seven prospectively observed children born to HIV-2 seropositive mothers showed no sign of infection. The lack of evidence of transmission of HIV-2 from mother to child is suggested to be due to the absence of marked immunodeficiency in this random sample of the general population.
点击下载:
PDF
(418KB)
返 回