Ultraviolet Spectroscopic Study of Cu2+Induced DNA Melting at Room Temperature
作者:
K.K. Deb,
期刊:
Spectroscopy Letters
(Taylor Available online 1981)
卷期:
Volume 14,
issue 5
页码: 385-393
ISSN:0038-7010
年代: 1981
DOI:10.1080/00387018108062597
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
Complexes of Calf thymus DNA with Cu2+ions have been studied using ultraviolet (UV) absorption spectroscopy to probe the binding and melting behavior of DNA in the complex at 25°C, causing a melting of DNA as effectively as heating to 100°C. This strengthens the concept of Cu2+binding to the DNA bases as recently demonstrated by Richard et al.1
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