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Modulation of Auditory Evoked Magnetic Fields by Benzodiazepines

 

作者: Christopher M Sinton,   John R McCullough,   Risto J Ilmoniemi,   Pierre E Etienne,  

 

期刊: Neuropsychobiology  (Karger Available online 1986)
卷期: Volume 16, issue 4  

页码: 215-218

 

ISSN:0302-282X

 

年代: 1986

 

DOI:10.1159/000118328

 

出版商: S. Karger AG

 

关键词: Auditory evoked fields;Benzodiazepine;Neuromagnetometry

 

数据来源: Karger

 

摘要:

The N1 and P2 components of the auditory evoked magnetic field were shown to be modified by the benzodiazepines diazepam and triazolam. Previous studies indicate that the electrical sources of these components are located in the auditory cortex, implying that benzodiazepines have a direct or indirect effect on neuronal activity at this level. The recorded changes were comparable to those previously reported using auditory evoked potential measurements. These results suggest that magnetic recordings may eventually be used as a sensitive, supplementary and location-specific measure of the central action of psychoactive substances.

 

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