Inhibition by Cyclopropane of Release of Norepinephrine, but not Dopamine-β-hydroxylase, from the Guinea-pig Vas Deferens
作者:
Michael Roizen,
Nguyen Thoa,
Jonathan Moss,
Irwin Kopin,
期刊:
Anesthesiology
(OVID Available online 1976)
卷期:
Volume 44,
issue 1
页码: 54-56
ISSN:0003-3022
年代: 1976
出版商: OVID
关键词: Anesthetics, gases, cyclopropane;Sympathetic nervous system, cyclopropane
数据来源: OVID
摘要:
Like halothane, cyclopropane reduces stimulation-induced release of norepinephrine, but not release of dopamine-β-hydroxylase, from the isolated guinea-pig vas deferens. The dissociation between transmitter release and enzyme release in the presence of cyclopropane may be the result of either an increase in the affinity of norepinephrine for binding sites on the vesicular membrane produced by cyclopropane, or a direct effect of cyclopropane on a mechanism of release of norepinephrine that could be controlled independently of release of dopamine-β-hydroxylase.
点击下载:
PDF
(169KB)
返 回