The Complications of Systemic Corticosteroid Therapy in the Elderly
作者:
T.P.L. Thomas,
期刊:
Gerontology
(Karger Available online 1984)
卷期:
Volume 30,
issue 1
页码: 60-65
ISSN:0304-324X
年代: 1984
DOI:10.1159/000212608
出版商: S. Karger AG
关键词: Hypertension;Corticosteroid therapy;Complications;Drug side effects;Osteoporosis
数据来源: Karger
摘要:
The complications of long-term corticosteroid therapy were reviewed in 100 elderly patients who were treated for chronic obstructive airways disease (n = 76), rheumatoid arthritis (n = 19) and ulcerative colitis (n = 5). The incidence of side effects was high (40%) and appeared to be dose-related. Osteoporosis (16%) and hypertension (12%) were the most common. Hypokalaemia occurred infrequently despite the fact that 69 patients were also prescribed diuretics. A further group of 36 patients receiving corticosteroids for polymyalgia rheumatica and giant cell arteritis also seemed to demonstrate a dose-related effect on the incidence of complications although this could not be confirmed statistically.
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