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CARDIAC AND BRONCHIAL β‐ADRENOCEPTOR ANTAGONISTIC POTENCIES OF ATENOLOL, METOPROLOL, ACEBUTOLOL, PRACTOLOL, PROPRANOLOL AND PINDOLOL IN THE ANAESTHETIZED DOG

 

作者: Herman H. Harms,   Albert J. G. Spoelstra,  

 

期刊: Clinical and Experimental Pharmacology and Physiology  （WILEY Available online 1978）
卷期: Volume 5, issue 1  

页码: 53-59

 

ISSN:0305-1870

 

年代: 1978

 

DOI:10.1111/j.1440-1681.1978.tb00651.x

 

出版商: Blackwell Publishing Ltd

 

关键词: acebutolol;β‐adrenoceptor blockade;atenolol;bronchial β‐adrenoceptors;cardioselective β‐adrenoceptor blockade;metoprolol;pindolol;practolol;propranolol

 

数据来源: WILEY

 

摘要:

SUMMARY1. The β‐adrenoceptor antagonists atenolol, metoprolol, acebutolol, practolol, propranolol and pindolol have been tested for their ability to reduce isoprenaline‐induced bronchodilation and tachycardia in the anaesthetized dog.2. Atenolol, metoprolol, acebutolol and practolol all possessed a similar degree of cardioselectivity in this animal m

 

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