Platelet plasma membrane in subjects with primary nocturnal enuresis: Effect of desmopressin
作者:
Pier Luigi Giorgi,
Rosamaria Fiorini,
Maurizio Biraghi,
Ahmad Kantar,
期刊:
Biology of the Cell
(WILEY Available online 1996)
卷期:
Volume 86,
issue 2‐3
页码: 135-137
ISSN:0248-4900
年代: 1996
DOI:10.1016/0248-4900(96)84776-9
出版商: Blackwell Publishing Ltd
关键词: enuresis;platelets;membrane fluidity;fluorescence
数据来源: WILEY
摘要:
Summry—Plasma membrane fluidity of platelets (PLT) obtained from subjects with primary nocturnal enuresis (PNE) and healthy controls was investigated before and after addition of desmopressin (DDAVP). Membrane fluidity was studied by measuring steadystate fluorescence anisotropy of 1‐(4‐trimethylammoniumphenyl)‐6‐phenyl‐1, 3, 5‐hexatriene incorporated into PLT plasma membrane. Our results show an increase in membrane fluidity at the surface level of PLT from subjects with PNE. Moreover, the addition of DDAVP induces a stable and significant decrease of membrane fluidity in both groups. These results suggest alterations of the lipid order in the exterior part of the PLT plasma membrane from pati
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