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Children of School Age: The Influence of Antiepileptic Drugs on Behavior and Intellect

 

作者: M. R. Trimble,   C. Cull,  

 

期刊: Epilepsia  （WILEY Available online 1988）
卷期: Volume 29, issue 1  

页码: 15-19

 

ISSN:0013-9580

 

年代: 1988

 

DOI:10.1111/j.1528-1157.1988.tb05805.x

 

出版商: Blackwell Publishing Ltd

 

关键词: Key Words: Epilepsy–Anticonvulsants–Drug‐induced abnormalities–Child–Intelligence–Behavior

 

数据来源: WILEY

 

摘要:

Summary:The role of antiepileptic drugs in behavior and cognitive function in children is well documented in the literature. In general, behavioral problems occur most frequently with phenobarbital and clonazepam, and appear least often with valproate and carbamazepine. Cognitive impairments occur with phenytoin, are less evident with valproate, and minimal with carbamazepine. Monotherapy, as with adults, leads to improvements in both cognitive abilities and behavior.

 

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