Prognostic Implications of Cutaneous Immunoglobulin Deposits In Systemic Lupus Erythematosus
作者:
Joel E. Bernstein,
Keyoumars Soltani,
Nersa Cristancho,
Andrew J. Aronson,
期刊:
International Journal of Dermatology
(WILEY Available online 1983)
卷期:
Volume 22,
issue 1
页码: 29-34
ISSN:0011-9059
年代: 1983
DOI:10.1111/j.1365-4362.1983.tb02109.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
ABSTRACT:The class of immunoglobulin (Ig) deposited at the dermal‐epidermal junction (DEI) of the skin in patients With systemic lupus erythematosus (SLE) has been proposed to have prognostic implications. The authors studied disease activity in 51 SLE patients with a positive lupus band. Patients with cutaneous IgM deposits had significantly more severe disease than those with only IgG or with mixed immunoglobulin deposits. While their data suggest an association between IgM depostis, severe disease and a poor prognosis, they urge caution in utilizing Ig deposits as a prognostic indicato
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