Integration of 1-nL sampling vials with a capillary sample introduction ultrathin slab gel electrophoresis system is described here. The low-volume sampling capabilities of capillary electrophoresis (CE) along with the small structural size make it an ideal sampling technique for these vials. A DNA restriction enzyme digest has been sampled and separated from these vials. A comparison of the nanovial DNA separation and a separation from a larger vial are virtually identical.