This article describes an endoscopic retrograde hemorrhoidal sclerotherapy technique that is well tolerated and associated with high patient satisfaction, low complication rates, and satisfactory long-term results. This therapy is best used when colonoscopy is performed, and the need for treatment of hemorrhoidal disease is identified prior to the procedure. Since conventional sclerotherapy equipment is used, the demands on the endoscopy staff and finances are lessened. This article also discusses the implications for nursing care and patient teaching associated with this procedure.