Total Synthesis of ( ± )-α-Cubebene and ( ± )-β-Cubebene
作者:
Edward Piers,
Ronald W. Britton,
William De Waal,
期刊:
Canadian Journal of Chemistry
(NRC Available online 1971)
卷期:
Volume 49,
issue 1
页码: 12-19
ISSN:0008-4042
年代: 1971
DOI:10.1139/v71-003
出版商: NRC Research Press
数据来源: NRC
摘要:
An efficient total synthesis of the racemic forms of the novel tricyclic sesquiterpenes α-cubebene (1) and β-cubebene (2) is described. The key step of this synthesis involved the cupric sulfate catalyzed intramolecular cyclization of the olefinic diazoketone3, which produced, in high yield, ( ± )-β-cubebene norketone (24) and ( ± )-1,6-epi-β-cubebene norketone (25), in a ratio of approximately 3:5, respectively.
点击下载:
PDF
(491KB)
返 回