“Synaptic” Ribbons and Spherules Lacking in the Pineal Gland of the European Hamster Appear After Ganglionectomy
作者:
M. Masson‐Pévet,
P. Pévet,
期刊:
Journal of Pineal Research
(WILEY Available online 1990)
卷期:
Volume 8,
issue 1
页码: 1-10
ISSN:0742-3098
年代: 1990
DOI:10.1111/j.1600-079X.1990.tb00801.x
出版商: Blackwell Publishing Ltd
关键词: pinealectomy;melatonin;5‐methoxytryptamine;pinealocytes;noradrenergic innervation
数据来源: WILEY
摘要:
“Synaptic” ribbons and spherules are typical organelles of the mammalian pinealocytes, that present quantitative day‐night variations parallel to pineal melatonin levels. The European hamster is a wild photoperiodic mammal whose pineal melatonin concentrations do not vary during the 24 hr light‐dark cycle. The aim of this study was thus to see if a rhythmic variation in synaptic structures was nevertheless present in this species. It was found that, in contrast to all of the photoperiodic species studied to date, the European hamster pinealocyte contains no ribbons, and virtually no spherules. Moreover, constant administration of melatonin does not result in the occurrence of these organelles; nevertheless, the pinealocytes have the potentiality to produce spherules and, to a lesser extent, ribbons, as they are observed in ganglionectomized animals and in the deep pineal of some hamsters after ablation of the superficial part of the gland. The formation of pineal synaptic structures, normally lacking in the European hamster, thus seems directly related to the noradrenergic innervation of th
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