Apoplexie Hypophysaire D’un Gonadotrophinome Et Test Au TRH/GnRH.
作者:
FrankartL.,
De HertoghR.,
DonckierJ.,
GilliardC.,
BuysschaertM.,
期刊:
Acta Clinica Belgica
(Taylor Available online 1995)
卷期:
Volume 50,
issue 3
页码: 163-170
ISSN:1784-3286
年代: 1995
DOI:10.1080/17843286.1995.11718441
出版商: Taylor&Francis
数据来源: Taylor
摘要:
SummaryPituitary apoplexy is a rare but sometimes dramatic complication of pituitary tumors. We report the case of a 64-year-old man with a macroadenoma who complained of a sudden and intense headache after a dynamic TRH (200 fig) and GnRH (100 fig) test. Two days later, he presented, an acute ophthalmoplegia with fever and deteriorating consciousness. Emergency CT scan showed contrast hypofixation compatible with necrosis of the adenoma. Surgical, tumoral decompression resolved quickly almost all symptoms. Immunohistochemical study of the tumor confirmed the diagnosis of gonadotropinoma. Several similar cases of pituitary apoplexy occurring after TRH or GnRH tests have been described the last ten years. As this test may sometimes confirm the diagnosis of gonadotropinoma, it should be performed with caution in cases of clinically non functioning pituitary macroadenoma.
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