Chemical and Physical Structure of Polymers as Carriers for Controlled Release of Bioactive Agents: A Review
作者:
Robert Langer,
Nikolaos Peppas,
期刊:
Journal of Macromolecular Science, Part C
(Taylor Available online 1983)
卷期:
Volume 23,
issue 1
页码: 61-126
ISSN:1532-1797
年代: 1983
DOI:10.1080/07366578308079439
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
In a controlled release system a drug, pesticide, or other bio-active agent is incorporated into a carrier, generally a polymeric material. The rate of release of the substance is determined by the properties of the polymer itself and is only weakly dependent on environmental factors (such as the pH of bodily fluids). Controlled release systems are capable of delivering substances slowly and continuously for up to several years.
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