Synthesis of Chiral [2.2.1] Cryptand Incorporating Methyl 4,6-O- [(S)-Phenyletrylidene]-α-D-Mannopyranoside Unit
作者:
Marek Pietraszkiewicz,
Janusz Jurczak,
期刊:
Journal of Carbohydrate Chemistry
(Taylor Available online 1985)
卷期:
Volume 4,
issue 3
页码: 429-434
ISSN:0732-8303
年代: 1985
DOI:10.1080/07328308508070192
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
Recently, we described the high-yield synthesis of chiral [2.2.1J cryptands incorporating carbohydrates. Models show that variations of substituents in the carbohydrate fragment, e.g. in 4,6-O-acetals, may lead to asymmetric modifications in close proximity to the molecular cavity of the ligand, and therefore, to changes in enantiomeric differentiation. We wanted to obtain the cryptand2with an axial phenyl group, as shown in Fig.1, which is in contrast to a cryptand (1) obtained earlier with an equatorial phenyl group.
点击下载:
PDF (167KB)
返 回