Effects of radiation on the cell proliferation kinetics of epithelial tissues—therapeutic implications
作者:
期刊:
The British Journal of Radiology
(WILEY Available online 1996)
卷期:
Volume 69,
issue 825
页码: 795-803
年代: 1996
DOI:10.1259/0007-1285-69-825-795
出版商: The British Institute of Radiology
数据来源: WILEY
摘要:
AbstractThe cell kinetic responses of the epithelia of the skin, oral mucosa and intestine to photon irradiation are reviewed. One of the fundamental assumptions made in the development of mathematical models, used to predict the acute response of normal tissues to changes in fractionation protocols, is “equal effect per fraction”. There is now accumulating cell kinetic data to indicate that this assumption is unlikely to be valid. The implications of these findings are discussed.
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