首页   按字顺浏览 期刊浏览 卷期浏览 4-Acetyl Annonacin and 4-Acetyl Xylomaticin: Two Novel Bioactive Mono-Tetrahydrofuran A...
4-Acetyl Annonacin and 4-Acetyl Xylomaticin: Two Novel Bioactive Mono-Tetrahydrofuran Annonaceous Acetogenins fromAsimina Longifolia(Annonaceae)

 

作者: Qing Ye,   Lu Zeng,   Guoen Shi,   Dean Evert,   JerryL. McLaughlin,  

 

期刊: Natural Product Letters  （Taylor Available online 1996）
卷期: Volume 8, issue 4  

页码: 291-298

 

ISSN:1057-5634

 

年代: 1996

 

DOI:10.1080/10575639608044910

 

出版商: Taylor & Francis Group

 

关键词: 4-acetyl annonacin;4-acetyl xylomaticin;annonaceous acetogenins;asimina longifolia;annonaceae

 

数据来源: Taylor

 

摘要:

Two novel bioactive acetogenins, 4-acetyl annonacin (1) and 4-acetyl xylomaticin (2), were isolated from the leaves and twigs ofAsimina longifoliaK. (Annonaceae) by directing the fractionation with the brine shrimp lethality test. 1 and 2 each has a mono-tetrahydrofuran (THF) ring with two flanking hydroxyl groups and an α, β-unsaturated γ-lactone with a 4-acetoxyl. The presence of acetoxyl groups is a feature rarely found in the Annonaceous acetogenins. 1 and 2 showed potent and selective cytotoxicities among six human tumor cell lines.

 

点击下载:  PDF (406KB)



返 回