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Enantiomeric Separations in Chromatography

 

作者: Daniel W. Armstrong,   Soon M. Han,   Willie L. Hinze,  

 

期刊: C R C Critical Reviews in Analytical Chemistry  (Taylor Available online 1988)
卷期: Volume 19, issue 3  

页码: 175-224

 

ISSN:0007-8980

 

年代: 1988

 

DOI:10.1080/10408348808542811

 

出版商: Taylor & Francis Group

 

数据来源: Taylor

 

摘要:

The resolution of enantiomers (nonsuperimposable, mirror-image isomers) has traditionally been considered one of the more difficult problems in separation science. Enantiomers have identical physical and chemical properties in an isotropic environment except that they rotate the plane of polarized light in opposite directions. A mixture containing equal amounts of enantiomers is referred to as a racemic mixture. Neither racemic mixtures nor solutions of achiral compounds are able to rotate the plane of polarized light.

 

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