Neuropeptide Y and cardiovascular regulation
作者:
Thierry Pedrazzini,
Hans Brunner,
Bernard Waeber,
期刊:
Current Opinion in Nephrology and Hypertension
(OVID Available online 1993)
卷期:
Volume 2,
issue 1
页码: 106-113
ISSN:1062-4821
年代: 1993
出版商: OVID
数据来源: OVID
摘要:
Neuropeptide Y is a vasoactive peptide and is widely distributed throughout the central and peripheral nervous systems. Neuropeptide Y is coreleased with noradrenaline by perivascular nerve endings. At high concentrations, it has a direct vasoconstrictor effect. In addition, it enhances the vascular effect of various agonists, including noradrenaline and angiotensin II. Moreover, neuropeptide Y has an inhibitory effect on renin secretion. This peptide may have an important role in cardiovascular regulation.
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