首页   按字顺浏览 期刊浏览 卷期浏览 Modulation of Phenotype and Cytoskeleton Architecture by lnterleukin-1 Alpha in Human O...
Modulation of Phenotype and Cytoskeleton Architecture by lnterleukin-1 Alpha in Human Osteoblast-Like Cells in vitro

 

作者: M. Bodo,   T. Baroni,   M. Calvitti,   F. Carinci,   N. Arena,   G. Venti,  

 

期刊: Cells Tissues Organs  (Karger Available online 1992)
卷期: Volume 145, issue 2  

页码: 156-161

 

ISSN:1422-6405

 

年代: 1992

 

DOI:10.1159/000147358

 

出版商: S. Karger AG

 

关键词: Interleukin-1α;Osteoblast-like cells;Morphology;Cytoskeleton;Fibronectin

 

数据来源: Karger

 

摘要:

Interleukin-1α, a growth factor produced by macrophages as well as many other types of cells, is able to modulate biosynthetic activities in bone cells. In this work, the authors show that the administration of interleukin-1α to osteoblas-like cells in vitro induces a marked change in cell morphology, which becomes dendritic, with a smaller cellular body and numerous prolongations. The morphological changes are also accompanied by an alterated expression in the pattern of cytoskeleton protein

 

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