Sustained Ventricular Tachycardia and Its Successful Prophylaxis During High-Dose Bolus Interleukin-2 Therapy for Metastatic Renal Cell Carcinoma
作者:
Leslie Oleksowicz,
Paul Escott,
Gail Leichman,
Edward Spangenthal,
期刊:
American Journal of Clinical Oncology: Cancer Clinical Trials
(OVID Available online 2000)
卷期:
Volume 23,
issue 1
页码: 34-36
ISSN:0277-3732
年代: 2000
出版商: OVID
关键词: Ventricular tachycardia;Interleukin-2;Renal cell carcinoma.
数据来源: OVID
摘要:
In the setting of interleukin-2 (IL-2) administration, tachycardias of ventricular origin are classified as serious, grade IV toxicities, necessitating the discontinuation of therapy. In this report, we describe a patient with renal cell carcinoma who experienced ventricular tachycardia while undergoing treatment with high-dose bolus IL-2. Prophylaxis with sotalol permitted the successful completion of his first cycle of treatment, without any recurrent rhythm disturbances.
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