Symmetrical Intrauterine Growth Retardation Is Not Symmetrical: Organ-Specific Gravimetric Deficits in Midtrimester and Neonatal Trisomy 18
作者:
Mark Paul Johnson,
Mason Barr, Jr.,
Faisal Qureshi,
Arie Drugan,
Mark I. Evans,
期刊:
Fetal Diagnosis and Therapy
(Karger Available online 1989)
卷期:
Volume 4,
issue 2-3
页码: 110-119
ISSN:1015-3837
年代: 1989
DOI:10.1159/000263432
出版商: S. Karger AG
关键词: Intrauterine growth retardation;Trisomy 18;Fetal organ weights
数据来源: Karger
摘要:
Models to predict normal fetal growth have been of limited accuracy. Abnormal growth is even more problematic. We have developed a mathematical modeling system based on observed body and brain weights to study fetal growth patterns in midgestational trisomy 18 fetuses. Third-degree polynomial-based analysis using observed fetal body and brain weights to generate predicted weights for various organ systems allows for the comparative study of growth patterns at various fetal weights and gestational ages. Our data suggest that what has been previously called symmetrical intrauterine growth retardation associated with aneuploid fetuses is really an asymmetrical pattern that is dynamic in nature and may change through the course of pregnancy.
点击下载:
PDF
(2761KB)
返 回