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Phase II study of aclarubicin in patients with breast cancer previously untreated with adriamycin

 

作者: S. Kerpel‐Fronius,   F. Gyergyay,   I. Hindy,   A. Decker,   S. Eckhardt,   I. Sawinsky,   Z. Mechl,   M. Nekulova,   K. Kolaric,   R. Tomek,   J. Röthig,  

 

期刊: European Journal of Haematology  （WILEY Available online 1987）
卷期: Volume 38, issue S47  

页码: 67-69

 

ISSN:0902-4441

 

年代: 1987

 

DOI:10.1111/j.1600-0609.1987.tb00026.x

 

出版商: Blackwell Publishing Ltd

 

数据来源: WILEY

 

摘要:

SUMMARYTwenty‐five breast cancer patients previously not exposed to adriamycin, were treated with 30 mg/m2/day aclarubicin for four consecutive days. Out of the 19 evaluable cases 1 CR and 2 PR were observed giving an overall remission rate of 16%. No cardiotoxicity was observed. Myelotoxicity and hair loss were mild (WHO grades 1 and 2). Grade 2 and 3 nausea and vomiting occurred frequentl

 

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