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Metallation of diazines.III. New synthesis of analogues of trimethoprim and of bacimethrin

 

作者: N. Ple,   A. Turck,   E. Fiquet,   G. Queguiner,  

 

期刊: Journal of Heterocyclic Chemistry  （WILEY Available online 1991）
卷期: Volume 28, issue 2  

页码: 283-287

 

ISSN:0022-152X

 

年代: 1991

 

DOI:10.1002/jhet.5570280213

 

出版商: Wiley‐Blackwell

 

数据来源: WILEY

 

摘要:

Abstract4‐Chloro‐2,6‐dimethoxypyrimidine was lithiated by lithium 2,2,6,6‐tetramethylpiperidide. The resulting lithio derivative was submitted to reaction with carbonyl derivatives, iodine and trimethyltin chloride. Synthesis of analogues of trimethoprim and of bacimetrin are r

 

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