Data from 94 Missouri reservoirs demonstrated a large interregional variation in total phosphorus (TP), total nitrogen (TN), algal chlorophyll (Chl), and suspended solids among the four physiographic provinces with numerous reservoirs. The interprovincial pattern for nutrients, algal biomass, and mineral turbidity was Ozark Highlands < Ozark Border ≃ Glacial Plains < Osage Plains corresponding to an interregional gradient between forest and agriculture as the dominant land cover. On the basis of TP most Missouri reservoirs were eutrophic (61%) or mesotrophic (21%) with few hypereutrophic (7%) or oligotrophic (11%). Statewide, water clarity was low (median Secchi depth 1.0 m) and more strongly related to non-volatile suspended solids (NVSS, R2= 0.80) than algal Chl (R2= 0.30). Summer mean values showed a curvilinear relation between Chl and TP (log10transformed) reaching an asymptote above ≃ 50 μg/L TP/L — a range where most reservoirs have high NVSS and low TN:TP. Nitrogen limitation, light limitation, or binding of phosphorus by non-algal suspended material may explain reduced Chl:TP ratios in turbid reservoirs. Survey data, however, do not distinguish the roles of differing limiting nutrients and light limitation in reservoirs with > 10 mg NVSS/L. Conventional lake management scenarios based on phosphorus control seem appropriate for Missouri reservoirs of low to moderate turbidity.