Effects of Chloramphenicol and Thiamphenicol on the Outcome ofChlamydia psittaciInfection in Chick Embryo
作者:
G. Allegri,
E. Lucidi,
G. Marca,
E. Borgogelli,
期刊:
Chemotherapy
(Karger Available online 1982)
卷期:
Volume 28,
issue 2
页码: 119-128
ISSN:0009-3157
年代: 1982
DOI:10.1159/000238066
出版商: S. Karger AG
关键词: Chloramphenicol;Thiamphenicol;Chlamydia psittaciinfection;Chick embryos;Metabolic pathways
数据来源: Karger
摘要:
The effects of chloramphenicol (CAP) and thiamphenicol (TAP) on the outcome of Chlamydiapsittaci infection in chick embryos were compared. CAP administered along with Chlamydia reduced embryo mortality rates but showed no appreciable effects when its injection was delayed. On the contrary, TAP caused a high rate of embryo survival in both experimental situations. Statistical analysis of the results showed that differences in the survival rates following CAP and TAP administration are significant. Metabolic pathways in chick embryos of the antibiotics assayed differed remarkably in that CAP undergoes a quicker inactivation, which could even justify the better activity showed by TAP.
点击下载:
PDF
(2614KB)
返 回