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Positive Association between the GABRA5 Gene and Unipolar Recurrent Major Depression

 

作者: L. Oruč,   G.R. Verheyen,   I.F. Furač,   S. Ivezić,   M. Jakovljević,   P. Raeymaekers,   C. Van Broeckhoven,  

 

期刊: Neuropsychobiology  （Karger Available online 1997）
卷期: Volume 36, issue 2  

页码: 62-64

 

ISSN:0302-282X

 

年代: 1997

 

DOI:10.1159/000119363

 

出版商: S. Karger AG

 

关键词: GABRA5 gene;Association analysis;Mood disorders

 

数据来源: Karger

 

摘要:

The gamma-aminobutyric acid (GABA) neurotransmitter system has been implicated in the pathogenesis of mood disorders. To test this hypothesis we carried out an association study between a dinucleotide repeat polymorphism in the GABAA receptor α5 subunit gene and bipolar and unipolar mood disorders. Our results suggest a possible involvement of this gene in unipolar but not in bipolar disorder

 

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