Lack of Pharmacokinetic Interactions Between Moxonidine and Digoxin
作者:
Günther Pabst,
Hans-Josef Weimann,
Werner Weber,
期刊:
Clinical Pharmacokinetics
(ADIS Available online 1992)
卷期:
Volume 23,
issue 6
页码: 477-481
ISSN:0312-5963
年代: 1992
出版商: ADIS
数据来源: ADIS
摘要:
The potential for pharmacokinetic interactions between moxonidine and digoxin at steady-state was investigated in 15 healthy male volunteers. Multiple oral doses of 0.2mg moxonidine twice daily and 0.2mg digoxin once daily were administered alone and in combination in a randomised 3-period crossover design. The drugs were administered for at least 5 days.The results indicate that neither moxonidine nor digoxin influences the pharmacokinetics of the other drug under steady-state conditions.
点击下载:
PDF
(2739KB)
返 回