Ovarian function in adolescent women following successful treatment for non‐Hodgkin's lymphoma
作者:
Daniel Green,
Daniel Yakar,
Martin Brecher,
Alan Lindsay,
Mary Voorhess,
Margaret MacGillivray,
期刊:
American Journal of Pediatric Hematology/Oncology
(OVID Available online 1983)
卷期:
Volume 5,
issue 1
页码: 27-32
ISSN:0192-8562
年代: 1983
出版商: OVID
数据来源: OVID
摘要:
ABSTRACTOvarian function was evaluated in eight adolescent women 1–90 months after completion of treatment for non-Hodgkin's lymphoma, which included a cyclophosphamide-containing combination chemotherapy protocol and radiation therapy. Two women received whole abdomen irradiation and both had ovarian failure. In contrast, none of six women who received combination chemotherapy and radiation therapy which did not include the abdomen had evidence of ovarian failure. These findings suggest that both the prepubertal and postpubertal ovary are relatively unaffected by this combination chemotherapy program which included cyclophosphamide and methotrexate.
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