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First-Derivative Spectrophotometric Assay of Timolol Maleate in Ophthalmic Solutions

 

作者: Maria IněsR.M. Santoro,   HyunSun Cho,   ErikaR.M. Kedor-Hackmann,  

 

期刊: Analytical Letters  （Taylor Available online 1996）
卷期: Volume 29, issue 5  

页码: 755-762

 

ISSN:0003-2719

 

年代: 1996

 

DOI:10.1080/00032719608001781

 

出版商: Taylor & Francis Group

 

关键词: Timolol maleate;first-order derivative spectrophotometry;ophthalmic solutions

 

数据来源: Taylor

 

摘要:

This research reports the application of derivative spectrophotometry to the determination of timolol maleate in ophthalmic solutions. A systematic approach developed for optimisation of the derivative order, graphical measurements and instrumental conditions led to the adoption of first-order spectrophotometry as a method with suitable precision and selectivity for the determination of timolol maleate in ophthalmic solutions without previous treatment.

 

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