Efforts aimed at showing that modern physics points to a truly transcendental factor as the explanation of the universe should be welcomed by those who have urged the teaching of physics in a broad cultural context. Those efforts may profit from the following guidelines: avoid the antiontological basis of the Copenhagen interpretation of quantum mechanics; make much of the reality of the universe and its enormous degree of specificity as revealed by general relativity and the cosmic background radiation; exploit Gödel’s incompleteness theorems against any grand unified theory proposed as if it were trueaprioriand necessarily; and realize that the design argument always presupposes the validity of the cosmological argument.