Gestational Changes in the Germinal Matrix of the Normal Rhesus Monkey Fetus
作者:
NICHOLAS LENN,
LEANNA WHITMORE,
期刊:
Pediatric Research
(OVID Available online 1985)
卷期:
Volume 19,
issue 1
页码: 130-135
ISSN:0031-3998
年代: 1985
出版商: OVID
数据来源: OVID
摘要:
To explain the reported predisposition to germinal matrix hemorrhage in premature infants, pathogenetically important morphological features of the germinal matrix should be present in the 3rd trimester and rapidly change near term. Such features were sought in this study of the germinal matrix and its vasculature in normal rhesus monkey fetuses. The matrix cells, glia, ependyma, and capillaries showed no important structural changes during the 3rd trimester. The terminal vein tributaries were greatly enlarged by 148 days, but cellular and collagen support in their walls was minimal at this time. The latter features developed by the final days of gestation. These findings do not support a structural immaturity or specialization of the germinal matrix predisposing to germinal matrix hemorrhage. Our results, therefore, support the recent emphasis on physiological parameters in the pathogenesis and prevention of germinal matrix hemorrhage.
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